UMDF Mitochondrial Medicine 2023

Meet our Scientific Organizing Committee and Speakers

Wednesday, June 28, Morning Platform: Mito Inflammation

Topic Title:
Nucleic Acid-mediated Mitonuclear Signaling



Topic Title:
PINK1- and Parkin-mediated Mitophagy and links to Inflammation and Neurodegeneration




Topic Title:
Extracellular ATP Signaling, Inflammation, and Mitochondrial Dysfunction


Topic Title:
OxPhos Defects, Inflammation and Hypermetabolism



Mitochondrial Medicine Society Wednesday Platform Session

Topic Title:
Circulating, Cell-free Mitochondrial DNA in Critical Illness


Topic Title:
Are Patients with Mitochondrial Diseases Hypermetabolic?


Topic Title:
Neurometabolic Regression Risk with Infection in Primary Mitochondrial Disease


Afternoon Session - Topic Title

Current Status of Biomarkers for Mitochondrial Disease


Wednesday, June 28, Afternoon Platform: Mysteries of mtDNA

Topic Title:
Mitochondrial-DNA Encoded Microproteins


Topic Title:
The Regulatory Interaction Between the Mitochondria and the Nucleus is Important for Health, Disease and Evolution Mitochondria are Central for Eukaryote Cellular Metabolism


Topic Title:
Stem Cells, Organoids, and Imaging Technologies to Delineate the Cellular and Molecular Changes in COVID-19


Topic Title:
mtDNA Haplogroup Disease Associations


Thursday, June 29, Morning Platform: Mito/Viruses

Topic Title:
Mitochondrion and Immune System



Topic Title:
Viral Exposures in Primary Mitochondrial Disease (PMD) Patients



Topic Title:
Mitochondrial Dysfunction Driven by Key microRNAs Contributing to Acute COVID-19 and Post-Acute Sequelae of COVID-19 (PASC)



Topic Title:
Coronaviruses: Intersection of Innate Immune and Unfolded Protein Responses


Topic Title:
Flaviviruses and Integrated Stress Response



Mitochondrial Medicine Society Thursday Platform Session

Topic Title:
Mitochondrial Disease and the Viral Exposome



Topic Title:
Through the Looking Glass: Viral Mimics and the Discovery of Novel Mitochondrial Functions



Topic Title:
Life and Death in Mitochondrial Disease: How Long Do We Have?




Thursday, June 29, Afternoon Platform: Mito Signaling

Topic Title:
Mitochondrial and Cellular Metabolism


Topic Title:
mtDNA Conformational Regulation


Topic Title:
MNRR1 Bicompartmental Mito Regulation


Topic Title:
MAT (Mitochondrial Augmentation Therapy) and MEPAN (Mitochondrial Enoyl CoA Reductase Protein-Associated Neurodegeneration)


Friday, June 30: Combined Sci/Med and Patient/Family Morning Sessions:

State of Mitochondrial Medicine and Clinical Trial Updates

Friday, June 30, Afternoon Session: Mito Genetic Therapy

Topic Title:
AAV-mediated Transduction of the Nuclear-coded Mitochondrial ANT1 Gene can Ameliorate Mouse Ant1-/- Pathology: a Step Toward the Treatment of Mitochondrial Cardiomyopathy


Topic Title:
Promises and Perils of mtDNA Gene Editing



Topic Title:
mtDNA & Deaminases


Topic Title:
Nuclear Transplantation


Saturday, July 1, Platform Session: Mito Transfer/Fatty Acid Synthesis

Topic Title:
Vesicular Transfer



Topic Title:
Nanotube Transfer



Topic Title:
Mitochondria Transfer and Leigh Syndrome


Topic Title:
Mitochondrial Transplantation: Clinical Application and Use


Topic Title:
mtFASII Pathway & Mouse Model


Topic Title
Mito FASII in OXPHOS Biochemistry
Topic Title:
Small Molecule Therapeutics