Leber’s Hereditary Optic Neuropathy
Leber’s Hereditary Optic Neuropathy, also called LHON or Leber’s (LAY-bers), is a rare condition which can cause sudden, profound, painless loss of central vision. While symptoms can begin at any age and in men or women, it is most common among men around age 20. Symptoms usually begin as painless blurriness in one eye quickly progressing to severe central vision loss, typically followed within a few months by similar symptoms in the second eye.
LHON is an extremely rare genetic disorder that is passed through the egg cell of the mother. While men cannot pass LHON on to their children, women carrying a LHON genetic mutation will pass it on to all of her children. These mutations can lead to the reduction in cellular energy production, which in turn results in cell damage and death of certain optic nerve cells. At this time, experts are unable to tell which, if any family members will develop symptoms, though on average 50% of men and 15% of women with a LHON mutation will lose vision in their lifetime.
LHON Related Websites
LHON Conference Calls
If you would like to download and listen to our latest conference call recorded on September 3, 2014, Click here.
You can also listen on your phone by dialing Toll free: 1-888-203-1112 and use Recording ID: 386454963
Consider making a donation to the UMDF LHON Project Fund for research, education and awareness projects.
To make your donation
Make your voice heard – contact your elected officials to ask them to support increased research for mitochondrial Disease, click here.
UMDF's LHON Ambassador
Lissa’s son Jeremy was diagnosed with LHON in 2009. As the UMDF’s LHON Ambassador, Lissa helps connect the LHON community to resources, information and most of all, hope.
Lissa and her husband Lionel have two other children, Julie and Eric.