Possible Symptoms
Mitochondrial Disease should be suspected when three or more organ systems are involved.
BRAIN
| Developmental delays | Migraines | Seizures |
| Dementia | Autistic Features | Atypical cerebral palsy |
| Neuro-psychiatric disturbances | Intellectual Disabilities | Strokes |
NERVES
| Weakness (may be intermittent) | Fainting | Absent reflexes |
| Neuropathic pain | Dysautonomia | Temperature Instability |
MUSCLES
| Weakness | Irritable bowel syndrome | Gastroesophogeal reflux |
| Cramping | Diarrhea or constipation | Hypotonia |
| Gastrointestinal problems | Pseudo-obstruction | Dysmotility |
KIDNEYS
| Renal tubular acidosis or wasting |
HEART
| Cardiac conduction defects (heart blocks) | Cardiomyopathy |
LIVER
| Hypoglycemia (low blood sugar) | Liver failure |
EARS & EYES
| Visual loss and blindness | Optic atrophy | Acquired strabismus |
| Ptosis | Ophthalmoplegia | Retinitis pigmentosa |
| Hearing loss | Deafness |
PANCREAS & OTHER GLANDS
| Diabetes | Exocrine Pancreatic Failure | Parathyroid failure |
SYSTEMIC
| Failure to gain weight | Unexplained vomiting | Respiratory problems |
| Fatigue | Short stature |