Possible Symptoms

Mitochondrial Disease should be suspected when three or more organ systems are involved.

BRAIN

Developmental delays Migraines Seizures
Dementia Autistic Features Atypical cerebral palsy
Neuro-psychiatric disturbances Mental retardation Strokes

NERVES

Weakness (may be intermittent) Fainting Absent reflexes
Neuropathic pain Dysautonomia Temperature Instability

MUSCLES

Weakness Irritable bowel syndrome Gastroesophogeal reflux
Cramping Diarrhea or constipation Hypotonia
Gastrointestinal problems Pseudo-obstruction Dysmotility

KIDNEYS

Renal tubular acidosis or wasting

HEART

Cardiac conduction defects (heart blocks) Cardiomyopathy

LIVER

Hypoglycemia (low blood sugar) Liver failure

EARS & EYES

Visual loss and blindness Optic atrophy Acquired strabismus
Ptosis Ophthalmoplegia Retinitis pigmentosa
Hearing loss Deafness

PANCREAS & OTHER GLANDS

Diabetes Exocrine Pancreatic Failure Parathyroid failure

SYSTEMIC

Failure to gain weight Unexplained vomiting Respiratory problems
Fatigue Short stature