Course Description 2018-04-27T14:38:50+00:00

Course Description

The United Mitochondrial Disease Foundation and Children’s Hospital Medical Center of Akron (CHMCA) have joined efforts to sponsor and organize a CME-accredited regional symposium. Mitochondrial diseases are more common than previously recognized and mitochondrial pathophysiology is now a recognized part of many disease processes, including heart disease, cancer, AIDS and diabetes. There have been significant advances in the molecular genetics, proteomics, epidemiology and clinical aspects of mitochondrial pathophysiology. This conference is directed toward the scientist and clinician interested in all aspects of mitochondrial science. The content of this educational program was determined by rigorous assessment of educational needs and includes surveys, program feedback, expert faculty assessment, literature review, medical practice, chart review and new medical knowledge. The format will include didactic lectures from invited experts intermixed with peer-reviewed platform presentations. There will be ample time for professional discussion both in and out of the meeting room, and peer-reviewed poster presentations will be given throughout the meeting. This will be a four-day scientific meeting aimed at those with scientific and clinical interests.


Neurologists, Geneticists, Researchers/Scientists, Pediatrics, Internal Medicine, Nephrologists, Cardiologists, Endocrinologists, Genetic Counselors, Advanced Practice Nurses, Physicians Assistants, RNs, Occupational Therapy, Physical Therapy and Speech-Language Pathology, Nutritional Therapy, and Residents/Fellows/Students.


  1. Learn about newly characterized mitochondrial enzymes.
  2. Become familiar with new insights into mitochondrial redox biochemistry and how this may be applied to developing new therapies for mitochondrial diseases.
  3. Learn how mitochondrial dysfunction affects the metabolic profile.
  4. Discover how imagining mass spectrometry can be used to understand mitochondrial function.
  5. Summarize how drugs can be developed that target them to the mitochondria.
  6. Describe the efforts of drug repurposing and how old medications may result in mitochondrial therapeutics.
  7. List the new developments in clinical trials in mitochondrial disease and distinguish the differences in their mechanisms of action.
  8. Demonstrate how the mitochondria can serve as an undesired target of pharmaceuticals and environmental exposures.



The Children’s Hospital Medical Center of Akron designates this live activity for a maximum of 19.75 AMA PRA Category I CreditsTM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Ohio State Medical Association (OSMA) through the joint providership of Children’s Hospital Medical Center of Akron and The United Mitochondrial Disease Foundation. The Children’s Hospital Medical Center of Akron is accredited by the OSMA to provide continuing medical education for physicians.

2018 Scientific Meeting – Confirmed Faculty

  • Vamsi K. Mootha, MD, 2018 Course Chair, Harvard Medical School, Boston, MA
  • Richard Caprioli, PhD, Vanderbilt University, Nashville, TN
  • Christopher J. Chang, PhD, UC Berkeley, CA
  • Sarah Elsea, PhD, Baylor College of Medicine, Houston, TX
  • Marni Falk, MD, Children’s Hospital of Philadelphia, PA
  • Grainne Gorman, PhD, Wellcome Trust Centre for Mitochondrial Research, UK
  • Dean P. Jones, PhD, Emory University, Atlanta, GA
  • Shana Kelley, PhD, University of Toronto, Canada
  • Kiyoshi Kita, PhD,  Nagasaki University, Japan
  • Carla Koehler, PhD, University of California, Los Angeles, CA
  • Daria Mochly-Rosen, PhD, Stanford University, Stanford, CA
  • Anne N. Murphy, PhD, University of California San Diego, La Jolla, CA
  • Mike Murphy, PhD, MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK
  • David J. Pagliarini, PhD, Morgridge Institute for Research at UW-Madison, WI
  • Sumit Parikh, MD, The Cleveland Clinic, Cleveland, OH
  • Ethan Perlstein, PhD, CEO, Perlara, San Francisco, CA
  • Pere Puigserver, PhD, Dana-Farber Cancer Institute, Boston, MA
  • Jared Rutter, PhD, University of Utah, Salt Lake City, UT
  • Rohit Sharma, MD, PhD, Massachusetts General Hospital, Boston, MA
  • Gerald I. Shulman, MD, PhD, Yale University School of Medicine, New Haven, CT
  • Jan Smeitink, MD, PhD, Radboud Center for Mitochondrial Medicine, Radboudumc, Nijmegen, The Netherlands
  • Anu Suomalainen, MD, PhD, University of Helsinki, Finland
  • Tanja Taivassalo, PhD, University of Florida College of Medicine, Gainesville, FL
  • Mark Tarnopolsky, MD, PhD, FRCP(C) McMaster University Medical Center, Ontario, Canada
  • Alice Ting, PhD, Stanford University, Stanford, CA
  • Kendall B. Wallace, PhD, University of Minnesota, Duluth, MN
  • Yvonne Will, PhD, Pfizer, Groton, CT
  • Philip Yeske, PhD, UMDF Science & Alliance Officer, Pittsburgh, PA


The potential for a conflict of interest may be considered to exist if a faculty member has any relevant interest or other relationship with the manufacturer of any commercial product discussed in her/his presentation.

As required by the Accreditation Council for Continuing Medical Education (ACCME), each speaker is required to complete a Speaker Disclosure Form which outlines any relationship the speaker has with any commercial company whose products he/she will be discussing. The prospective audience must be made aware of the affiliation/financial interest by an acknowledgment in the program or syllabus or in the faculty listing.

The intent of this policy is not to prevent a speaker from making a presentation. It is intended only that any potential conflict of interest should be identified openly so that the listeners may form their own judgments about the presentation with the full disclosure of the facts.

To come – presenters who have a financial arrangement or affiliation with an organization or company:

Once updated, remaining speakers and planning committee have indicated that they have no relevant financial interest in any pharmaceutical or medical device company and do not intend to discuss any off-label uses of medications or medical devices in their presentations. Others not listed will provide disclosures onsite if applicable.

2018 Scientific Symposium Planning Committee

  • Vamsi K. Mootha, MD, 2018 Course Chair, Harvard Medical School, Boston, MA
  • Bruce H. Cohen, MD, 2018 CME Chair, Akron Children’s Hospital, Akron, OH
  • William Copeland, PhD, 2017 Course Co-Chair, NIEHS, Research Triangle Park, NC
  • Marni Falk, MD, The Children’s Hospital of Philadelphia, Philadelphia, PA
  • Amy Goldstein, MD, Children’s Hospital of Philadelphia, Philadelphia, PA
  • Larry Grossman, PhD, Wayne State University School of Medicine, Detroit, MI
  • Adam Hartman, MD, NINDS/NIH, Rockville, MD
  • Amel Karaa, MD, Massachusetts General Hospital, Boston, MA
  • Carla Koehler, PhD, University of California Los Angeles, Los Angeles, CA
  • Giovanni Manfredi, MD, PhD, Weill Cornell Medicine, New York, NY
  • Robert K. Naviaux, MD, PhD, UCSD, San Diego, CA
  • Sumit Parikh, MD, The Cleveland Clinic, Cleveland, OH
  • Russell Saneto, DO, PhD, Course Chair, Seattle Children’s Research Institute, Seattle, WA
  • Peter Stacpoole, PhD, MD, University of Florida, Gainesville, FL
  • Keshav Singh, PhD, University of Alabama at Birmingham, AL
  • Philip E. Yeske, PhD, UMDF Science & Alliance Officer, Pittsburgh, PA
  • Kara Strittmatter, CMM, MA, UMDF Meeting Event Director, Columbus, OH


For more information on continuing education (CME), please email or call 888-317-UMDF.

Symposium Links

Every time I attend it gets better and better . . . speakers, networking, etc. and especially the last 2-3 years, clinical trial/studies part of program. Great to see more in attendance!
Gail Wehling, Illinois
Talking with doctors and researchers! So helpful. Teen sessions… My kids loved feeling a part of a group of teens that were “like them.”
Laura Ursiny, Michigan
For our family, this symposium was transformational. We have been given hope. For our daughter, she now has friends who get her!
Patti Wood, California